CURRICULUM VITAE
MARK LAMONT HOLTSMAN
Business Address
UC Davis Medical Center
2317 Stockton Blvd
Sacramento, CA 95817
(916) 765-6594
EDUCATION
Doctor of Pharmacy University of the Pacific
Conferred in May, 1987 School of Pharmacy
Bachelor of Science, Biochemistry University of California, Davis
Conferred in June, 1984
LICENSURE
California Pharmacist License No. 41434 Expiration Date 04/30/13
PROFESSIONAL EXPERIENCE
January 2004 CO-DIRECTOR, INPATIENT PAIN SERVICE
to present PAIN MANAGEMENT SERVICE PHARMACIST
UC Davis Medical Center
Coordinator of Clinical Services: Patricia Parker, Pharm.D.
Chief, Division of Pain Medicine: Scott Fishman, M.D.
January 2002 PAIN MANAGEMENT SERVICE PHARMACIST
to December 2003 UC Davis Medical Center
Coordinator of Clinical Services: Jeff King, Pharm.D.
November 1999 DIRECTOR, MEDICAL LIAISONS
to December 2001 North West Region
Purdue Pharma L.P.
Senior Director, Medical Liaisons: Joseph DaBronzo, Pharm.D.
July 1996 PAIN MANAGEMENT SERVICE PHARMACIST
to November 1999 UC Davis Medical Center
Manager, Pharmacy Department: David Heeren, Pharm.D.
August 1991 OPERATING ROOM PHARMACIST
to June 1996 UC Davis Medical Center
Associate Director: David Heeren, Pharm.D.
April 1989 MICU/CCU SATELLITE PHARMACIST
to August 1991 UC Davis Medical Center
Director: Nabil Musallam, R.Ph., M.S.
August 1988 NIGHT/POISON INFORMATION PHARMACIST
to April 1989 UC Davis Medical Center
Director: Nabil Musallam, R.Ph., M.S.
July 1987 RESIDENT IN CLINICAL PHARMACY
to June 1988 University of California, San Francisco
Director: Eric T. Herfindal, Pharm.D., M.P.H.
HONORS
2008 Long Award for Teaching Excellence
1987 Mylan Pharmaceuticals Excellence in Pharmacy Award
1987 Smith, Kline, and French Laboratory Award For Superior Achievement In Clinical Pharmacy
1987 The Merck Award
1987 Phi Kappa Phi Honor Society
1986 Thomas J. Long and Muriel T. Long Endowed Pharmacy Scholarship
1985 Rho Chi Honor Society
TEACHING EXPERIENCE
January 1994 Clinical Professor
to Present Department of Anesthesiology and Pain Medicine
University of California, Davis
April 1989 Clinical Professor
to Present School of Pharmacy
University of California, San Francisco
July 1987 Preceptor, Inpatient and Outpatient
to June 1988 Clinical Clerkship
University of California, San Francisco
Fall 1987 Conference Leader
Therapeutics Course
University of California, San Francisco
PUBLICATIONS
Opioid Dose Evaluation for Breakthrough Pain and Its Proportionality to the Total Opioid Dose in Cancer Patients with Chronic Opioid Use. Nguyen M, and Holtsman M. Abstract 196 Pain Med. 2009 Jan;10(1):247
Commentary on Dr. Heit and Dr. Gilson’s letter to the Drug Enforcement Administration. Does your Pharmacist Interpret a New Federal Standard in a Manner that Can Make your Patient Suffer in Pain? Holtsman M. Pain Med. 2008 Oct;9(7):927.
Fentanyl buccal tablets effective for pediatric patient with episodic pain secondary to ulcerative coloitis. Holtsman ML, Wania-Galicia L, and Williamson D. J Pain 9(4) Supp 1 April 2008 Page 39 Abstract 253 Presented at American Pain Society Annual Meeting May 2008
Ending triplicate prescription use in California: The effect on prescribing patterns of controlled substances, Cello R, Holtsman M, and Mowers R. J Pain, April 2007: 8:4:S86 Abstract
Evaluating the effectiveness of a pharmacist-managed pain consult service in postoperative knee replacement patients. Yacoub, C, Liang L, Ryu J, Thongsinthusak T, and Holtsman M. Abstract 290, ACCP Annual Meeting, St. Louis, Missouri October 2006
Holtsman M, Fishman SM. Opioid Receptors. In: Benzon HT, Raja SN, Molloy RE, Liu SS, Fishman SM eds.
Essentials of Pain Medicine and Regional Anesthesia. Philadelphia: Elsevier Churchill Livingstone; 2005: 87-93.
Fishman SM, Condon J, Holtsman ML. Common Opioid-Related Side Effects. In: Warfield CA, Bajwa ZH eds. PRINCIPLES AND PRACTICE OF PAIN MEDICINE. New York: McGraw-Hill; 2004: 612-615.
Repackaging Ketorolac Tromethamine Syringes, Garvey M, Holtsman M.
Ann Pharmacother, November 1998: 32:1252
Less Constipation, Sedation with Transdermal Fentanyl Than Sustained-Release Morphine, .
Holtsman ML. Pharmacy Practice News, November 1997.
More Than $900,000 Saved Per Year Using Physician-Directed Pharmaceutical Guidelines, .
Physician-Directed Pharmaceutical Guidelines, Holtsman ML. Pharmacy Practice News, November 1997.
Researchers Find Addition of Ketorolac to Morphine PCA Reduces
Postoperative Myocardial Ischemia, Holtsman ML. Pharmacy Practice News October 1997.
Cost-Effectiveness of Aprotinin Questioned, Holtsman ML. Pharmacy Practice News, August 1997.
Barrier Isolation Technology Said to Offer Pharmacists a Cost-Effective
Alternative to Clean Rooms, Holtsman ML Pharmacy Practice News May 1997.
Epidural Morphine With Butorphanol For Post Operative Analgesia
Tsang BK, Holtsman ML, et al. Regional Anesthesia March-April 1995
Volume 20 Number 25.
Holtsman ML, Guharoy S. Cholelithiasis Part 1. The Pathogenesis of
Gallstone Disease. J Pharm Technol 1987;3:142-6.
Guharoy S, Holtsman ML, Nath B. Cholelithiasis Part 2. Treatment
J Pharm Technol 1987;3:147-154.
Holtsman ML. Case 50 Glaucoma In: Hart LL, Gourley DR, Herfindal ET,
eds. Workbook for Clinical Pharmacy and Therapeutics. Baltimore:
Williams and Wilkins; 1988: 107-108.
RESEARCH
The Analgesic Efficacy and Therapeutic Onset of Analgesia of IV and IM Ketorolac 15mg and Ketorolac 30 mg and Oral Ibuprofen 800mg in the Emergency Room: A Comparative Study
Primary Investigator with Mohdhar Habib, Tomas Brofeldt, M.D., Sam Turnipseed, M.D., Steven Richeimer, M.D., and Stephen Macres, M.D.
Oral Naltrexone for Reduction of Epidural Opiate Side Effects
Primary Investigator with Brian Tsang, M.D.
Stability of Naltrexone Hydrochloride in a Liquid Formulation
Primary Investigator with Ron Duncan.
Comparison of Epidural Morphine vs. Epidural Morphine with Butorphanol for Post-Op Pain Control.
Co-investigator with Karen Pardo, Pharm.D., Mike Levin, M.D., John Eisele, M.D.
and Wayne Gannaway, Pharm.D.
PROFESSIONAL ASSIGNMENTS AND ACTIVITIES
January 1994 to Member
November 1999 Pain Management and Education Committee
University of California, Davis Medical Center
January 1995 to Chairman
November 1999 Multidisciplinary Epidural CQI Workgroup
University of California, Davis Medical Center
January 1995 to Co-Chair
April 1996 Multidisciplinary Pediatric PCA CQI Workgroup
University of California, Davis Medical Center
July 1993 to Member
Present Multidisciplinary PCA CQI Work Group
University of California, Davis Medical Center
July 1993 to Member
Present Pharmacy CQI Committee
University of California, Davis Medical Center
July 1992 to Member
January 1994 Committee To Monitor and Evaluate Control of Pain
University of California, Davis
February 1990 to Chairman
April 1993 PCA Infusion Pump Advisory Committee
University of California, Davis Medical Center
January 1990 Member
Resident Selection Committee
University of California, Davis Medical Center
February 1988 Member
Resident Selection Committee
University of California, San Francisco Medical Center
February 1988 Faculty Interviewer
University of California, San Francisco
December 1987 to Chief Pharmacy Resident
February 1988 University of California, San Francisco Medical Center
July 1987 to Member
September 1987 Research Committee, Division of Clinical Pharmacy
University of California, San Francisco
December 1986 to Member
May 1987 Faculty Evaluation Committee
University of the Pacific
LECTURES AND PRESENTATIONS
November 2008 Treating Episodic Pain in Patients with Opioid-Induced Hyperalgesia: How Did We Wind Up Here? 19th Annual UC Davis Anesthesiology Update, Monterey, CA
April 2008 Emerging Issues in Pain Management, UC Davis Pharmacology Update 2008, Napa, CA
November 2007 Opioid Conversion Concepts: A Pain Management Pharmacists Perspective, 18th Annual UC Davis Anesthesiology Update, Monterey CA
November 2003 Opioid Conversion Concepts in Chronic Pain Management
Sacramento Valley Society of Health-system Pharmacists
Sacramento, CA
October 2003 Managing Acute Pain Episodes in Patients on Chronic Opiates
Seminar 2003
California Society of Health-system Pharmacists
Sacramento, CA
October 2003 Opioids
UC Davis Review and Update of Pain and Palliative Medicine
Napa, CA
May 2003 Managing the Symptoms of Suffering
UC Davis Pain Management Review
Sacramento, CA
March 2003 Managing Acute Pain in Patients on Chronic Opioid Therapy
Anesthesiology Grand Rounds
UC Davis Medical Center
Sacramento, CA
January 2003 New Options for Pain Control in Neuropathic Pain
UCDMC Pharmacology 2003
Phoenix, AZ
January 2003 New Options for Pain Control in Palliative Care
UCDMC Pharmacology 2003
Phoenix, AZ
October 2002 Managing the Symptoms of Suffering
UC Davis Pain Management Review
San Francisco, CA
March 2002 Opiate Conversion Concepts
University of the Pacific, School of Pharmacy
Stockton, CA
February 2002 Opiate Conversion Concepts
University of the Pacific, School of Pharmacy
Stockton, CA
June 2001 Analgesic Pharmacology and Pharmacotherapy
Group Health Cooperative,
Seattle, WA
June 2001 Acute Pain Management
University of the Pacific, School of Pharmacy
Stockton, CA
June 2001 Pain Management For Pharmacists
University of the Pacific, School of Pharmacy
Stockton, CA
May 2001 Pain Management For Pharmacists
Vancouver Pharmacists Association
Vancouver, WA
March 2001 Opioid Induced Itching
Pain Interest Group, University of California, San Francisco
San Francisco, CA
March 2001 Pain Management For Pharmacists
Alaska Pharmacists Association Annual Meeting
Anchorage, AK
March 2001 Bioethics, the Law and Medicine, Framing the Debate about ethical treatment of Pain
University of California, Davis Cancer Center
January 2001 Pain Management Overview
Grand Rounds, San Joaquin County Medical Center
Stockton, CA
November 2000 Pain Management in the Elderly
Alameda County Pharmacists Association
San Leandro, CA
November 2000 Pain Management in the Elderly
Marin County Pharmacists Association
San Rafael, CA
October 2000 Revised JCAHO Pain Management Standards
University of Washington Roosevelt Pain Center
Seattle, WA
October 2000 Opiate Pharmacology
University of California, Davis Pain Management Center
Sacramento, CA
September 2000 Working Together To Meet The Joint Commission’s Pain Standards Interactive Workshop
University of California, San Francisco
August 2000 Revised JCAHO Pain Management Standards
Stanford University Hospital
Palo Alto, CA
July 2000 Pain Management For Pharmacists
Central Valley Society of Health System Pharmacists
Modesto, CA
June 2000 Pain Management For Pharmacists
QUATRA Chapter, California Society of Health System Pharmacists
Los Gatos, CA
May 2000 Regulatory Issues Surrounding the Legitimate Prescribing of Opioids For Chronic Pain
Ada County Medical Society
Boise, ID
April 2000 Optimizing Analgesic Pharmacotherapy
Pocatello Pharmacists Association
Pocatello, ID
February 2000 Analgesic Pharmacology and Pharmacotherapy For Neuropathic Pain
Sacramento Valley Oncology Nursing Society
Sacramento, CA
November 1999 Pharmacology
West Coast Center for Palliative Education
UC Davis Cancer Center
August 1999 Drug Therapy in Pain Management
Family Nurse Practitioner Therapeutics Course
University of Phoenix, Sacramento
August 1999 Pharmaceutical Care Challenges in Pain Management
Willamette Valley Hospice
Salem, Oregon
June 1999 Pharmaceutical Care Challenges in Pain Management
Sacramento Valley Society of Hospital Pharmacists
Radisson Hotel, Sacramento, California
April 1999 Minimizing Opioid Induced Itching
Anesthesia Pain Service
Pain Management Center
UC Davis Health System
April 1999 Drug Therapy In Pain Management
Family Nurse Practitioner Therapeutics Course
University of Phoenix
April 1999 Optimizing Analgesia
Pharmacology Update
Center For Continuing Nursing and Medical Education
UC Davis Health System
December 1998 Optimizing Analgesia
Pharmacology Update
UC Davis Health System
June 1998 Analgesia, Pain and Inflammation Control
UC Davis Family Nurse Practitioner/Physician Assistant Program
UC Davis Health System
June 1998 Do’s and Don’t of Narcotic Prescription Writing
7th Annual UC Davis Conference on the Primary Care
Treatment of Pain at Yosemite
UC Davis Health System
March 1998 Drug Therapy in Pain Management
Family Nurse Practitioner Therapeutics Course
University of Phoenix
December 1997 Do’s and Don’ts of Narcotic Prescription Writing
Noon Conference
Family Practice Residency Program
University of California, Davis, Medical Center
October 1997 Drug Therapy in Chronic Pain Management
Noon Conference
Family Practice Residency Program
University of California, Medical Center
October 1997 Pain Management: Commonly Used Pediatric Analgesics and Pharmacologic Strategies
Pediatric Post-Surgical Care and Pain Management
Center for Continuing Nursing and Medical Education
University of California, Davis Medical Center
June 1997 Do’s and Don’ts of Narcotic Prescription Writing
6th Annual Pain Conference at Tahoe
University of California, Davis Medical Center
May 1997 Drug Therapy in Pain Management
Nurse Practitioner Program
University of California, Davis Medical Center
October 1996 Optimizing Analgesia
Internal Medicine Grand Rounds
University of California, Davis Medical Center
May 1996 Drug Therapy in Pain Management
Pharmacology Course
Nurse Practitioner Program
University of California, Davis Medical Center
April 1996 Do's and Don'ts of Narcotic Prescription Writing
5th Annual Pain Conference at Yosemite
University of California, Davis Medical Center
March 1996 Low Dose Ketorolac Analgesia
Pharmacist Conference
University of California, Davis Medical Center
January 1996 PCA Dosing Guidelines/PCA Order Form Update
Ob/Gyn Grand Rounds
University of California, Davis Medical Center
June 1995 Will Tramadol Replace Acetaminophen With Codeine
University of Phoenix
May 1995 Patient Controlled Analgesia - Optimizing Analgesia While
Minimizing Side Effects
Nursing Center for Education
University of California, Davis Medical Center
November 1994 Conscious Sedation Pharmacology
Nursing Center for Education
University of California, Davis Medical Center
October 1994 Patient Controlled Analgesia and Adjunct Analgesics
Sutter Lakeside Hospital
October 1994 Patient Controlled Analgesia: A Tool to Control Acute Pain
Internal Medicine Noon Conference
University of California, Davis Medical Center
September 1994 Neonatal Equianalgesic Pain, Sedation and the Withdrawing Neonate
University of California, Davis Medical Center
September 1994 Complications of Epidural Analgesia
Pharmacists Conference
University of California, Davis Medical Center
September 1994 Neonatal Equianalgesia, Pain, Sedation and the Withdrawing Neonate
Nursing Center for Education
University of California, Davis Medical Center
July 1994 Oral Naltrexone for Reduction of Epidural Opiate Side Effects
Orthopedic Surgery Nurses
University of California, Davis Medical Center
July 1994 Oral Naltrexone For Reduction of Epidural Opiate Side Effects
East 4 Nurses
University of California, Davis Medical Center
May 1994 Complications of Epidural Analgesia
Post Anesthesia Nurses Association of California
University of California, Davis Medical Center
March 1994 Does Pain Management Have To Be A Pain
PACU Nurses
University of California, Davis Medical Center
February 1994 Adjunct Analgesia
Ambulatory Care Pharmacists and Residents
University of California, Davis Medical Center
December 1993 Immunosuppressive Therapy In Solid-Organ Transplantation
Nursing Challenges in Transplantation
University of California, Davis Medical Center
November 1993 Conversion To New Standard Concentrations And Orders For PCA/Epidural Analgesia
Anesthesia/Surgery Joint Grand Rounds
University of California, Davis Medical Center
October 1993 Pain Management For Physical Therapy
Department of Physical Therapy
University of California, Davis Medical Center
June 1993 Does Pain Control Have To Be A Pain?
Nursing Brown-Bag Lecture Series
University of California, Davis
April 1993 Pain Task Force/Challenges of Acute Pain Service
Anesthesia Grand Rounds
University of California, Davis
February 1993 Review of Medications Used In Transplantation
Transplant Support Group
University of California, Davis
July 1992 Narcotic Control, Controlled Substance
Schedules and Physician Responsibility
Anesthesia Resident Conference
University of California, Davis
April 1992 Cardioplegia and Transplant Preservation Solutions
Pharmacist Technician Conference
University of California, Davis
January 1992/1993 Opioid Analgesics, General Anesthesia and Local Anesthetics
Pharmacology Course
Nurse Practitioner Program
University of California, Davis
January 1990 Diuretic Agents
Pharmacology Course
Nurse-Practitioner Program
University of California, Davis
March 1988 Emergency Drug Use in Code Blue Response
Weekly Discussion Seminars
Ambulatory Care Medicine
University of California, San Francisco
March 1988 Peptic Ulcer Disease. An Infectious Disease?
Pharmacy Grand Rounds
University of California, San Francisco
November 1987 Digoxin Use in Atrial Fibrillation: A Review
Cardiology Staff Physicians, House Officers,
and Medical Students.
University of California, San Francisco
PROFESSIONAL ASSOCIATION MEMBERSHIPS
American Pain Society
American Academy of Pain Medicine
PROFESSIONAL ASSOCIATION ASSIGNMENTS AND ACTIVITIES
1987 Moderator, Seminar 87, California Society of Hospital Pharmacists
1988 Staff, Annual Meeting, American Society of Hospital Pharmacists
1993 Moderator, Western States, Residents and Preceptors Conference
2000 Chair, Pharmacist Education and Training Subcommittee, American Pain Society
REFERENCES AVAILABLE UPON REQUEST
